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Wraparound support : Includes: Nutrition and diet guidance Physical activity plans Behavioural support (minimum 9 months) Monitoring : Monthly reviews during the early phase Ongoing follow-up thereafter Treatment review : At 6 months, you must have lost at least 5% of your starting weight to continue treatment

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High PKM1/PKM2 ratios inhibited the glycolysis rate and elevated glucose flux into oxidative phosphorylation (103)

(2017) 6:e28766