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This reaction is catalyzed by 6-phosphogluconate dehydrogenase

The pentose phosphate pathway is sometimes described as a shunt, rather than a pathway, because when pentoses are not needed for biosynthetic reactions, the pentose phosphate intermediates are recycled back into the mainstream of glycolysis by conversion into Fru-6-P and glyceraldehyde-3-phosphate

OTC medications may also improve symptoms, though you should always consult a healthcare provider before adding anything new (especially a drug) to your routine