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White, brown, beige/brite: different adipose cells for different functions
In the STEP trials, participants taking semaglutide lost significantly more weight than those on placebo, with weight loss continuing for the full duration of treatment
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Results Four studies, with 28,827 patients (14,870 tirzepatide/13,928 semaglutide), mean age of 55.7 years (52.0 to 63.7) and mean followup of 35.9 weeks (23.6 to 44.6), were included in this study
A team from Maccabi Health Services retrospectively analysed data on the use of semaglutide in 200,000 patients from the Maccabi diabetes registry
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