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In our population, the latter group was more represented, thus confirming previous evidence that not all obese PCOS are similar in terms of response to glucose load (19)

Thus, any impairment to either of the system Xc -glutathione-GPX4 axis compromises the conversion of lipid peroxides to the corresponding alcohols, ultimately hampering the GPX4 antioxidant effect and giving rise to ferroptosis ( Nuclear factor erythroid 2-related factor 2 (Nrf2) has been found to be a key regulator in inhibiting ferroptosis

These molecules are hypothesized to potentially play significant roles in cell growth, migration, and angiogenesis

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