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The roots, leaves, and basal stem of this plant contain various alkaloids, including the well-known chemically used anti-carcinogenic alkaloids vinblastine, vindoline, vindolidine, vindolicine, vindolinine, vindogentianine, and vincristine (9)

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Studies in animal models of chronic ethanol feeding have shown mitochondrial functional modifications, whereas patients with alcoholic steatohepatitis (ASH) had mitochondria with morphological and functional abnormalities [69,70,71]