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7.4.1.2 RNA-based therapeutic approaches RNA-based therapeutics, including miRNA mimics and long non-coding RNA-targeting therapies, hold substantial potential for reversing spermatogenic defects caused by EEDs (146)

These include helping repair skin and calming inflammation

We systematically reviewed research on MNM-based therapies for specific conditions, including peptic ulcers, IBD, PC, CRC, and diabetes, integrated progress across these diseases, and discussed the potential clinical translation of MNMs

However, while oral supplements are an option, they have limited bioavailability

Repurposing drugs already approved for other conditions has the advantage of providing data and experience from previous research and practical use so we already know a lot about real-world effectiveness in other diseases and side effects, Carrillo added