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Animal studies further support this notion, demonstrating that combining MIA with postnatal stress produces synergistic effects on behavior and glial phenotypes (Giovanoli et al., 2013

In reality, GGT is not just a liver enzyme

Glutathione S-transferase activity was measured as described by Habig et al

2024;327(1):E103-E110

In addition to multifocal lesions in MS, in a recent study using fluorescence spectroscopy using the solvatochromic lipid probe Nile Red, we reported diffuse changes in myelin lipid polarity in otherwise normal-appearing MS white matter, which was particularly pronounced in the periventricular areas, again supporting the notion of a myelin toxin circulating in the CSF