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In combination with the general detection of only thioacetal B and the starting material SM in the hydroformylation crude, we hypothesize that EDT traps the cyclized species A to form thioacetal B either by direct engagement or indirectly via an equilibrium with allysine A under the harsh cleavage conditions

For patients with type 2 diabetes, this typically results in lower average blood glucose levels and reduced postprandial glucose excursions

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One important limitation: the clinical weight loss results were modest