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As the supply shortfall has driven explosive growth in the black market for GLP-1 drugs, the FDA has temporarily allowed production of what are known as compounded versions of the drugs

The mechanism is fundamentally about caloric restriction, not specific to any one drug

veterans with type 2 diabetes found that semaglutide initiators had about a two-fold higher NAION risk compared with SGLT2 inhibitor initiators, although the absolute risk remained low

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