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In the process, glutathione is converted to its oxidized form, glutathione disulfide (GSSG), also called L-()-glutathione

Preclinical studies suggest a synergistic effect between membrane-active agents, stress-pathway inhibitors, and conventional antifungals ( Designing the delivery system should focus on achieving high local concentrations with low systemic exposure factors, such as slow-release catheter coatings or mucoadhesive gels, to fully leverage activity against embedded persisters and minimize toxic effects on the host (Pedro et al., 2023)

Only when previous methods have not produced the intended outcomes should semaglutide be considered

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Sibai BM, Viteri OA