D., VandeBerg, J
For example, hyperglycemia increases the O-GlcNAc modification of calcium/calmodulin-dependent protein kinase II (CaMKII), which in turn leads to the autonomous activation of CaMKII ( 2+ leakage, improved cardiac contractility, and reduced arrhythmia events ( Figure 2 In summary, calcium plays an important role in cardiac dysfunction caused by ROS derived under the condition of hyperglycemia
In terms of oxidative stress indicators, DHT treatment significantly increased MDA levels while decreasing SOD and GSH-PX activities, and PLB treatment significantly reversed these changes and alleviated oxidative stress (Fig
Structurally modulated formation of cyanine J-aggregates with sharp and tunable spectra for multiplexed optoacoustic and fluorescence bioimaging
Guarducci C, Nardone A, Russo D, Nagy Z, Heraud C, Grinshpun A, et al