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Pathophysiology of Pain and Infertility Associated with Endometriosis Mechanism of Pain: Many studies have noted the presence of increased proinflammatory cytokines and growth factors in endometriosis that are closely related to pain sensation (i.e

New symptoms like persistent redness, texture changes, or sensitivity have developed

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Over this short treatment period, a significant improvement in pain assessed by VAS as well as sleep disturbance was noted