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No 420: Acute Oral Toxicity-fixed Dose Method

Mice deficient in mdr1a and mdr1b revealed that P-gp knockout was not fatal in mice but likely increased the assimilation and neurotoxicity of various drugs ( mdr1a / mdr1b and mrp1 genes demonstrated that P-gp and MRP1 transporters were responsible for the development of resistance to anthracyclines, taxol, and vinca alkaloids (245)

Aherne C, Rapp C, Collins C, Mcnamee E, Jedlicka P, Eltzschig H (2016) P-124 migration of CD4 Th1 T cells to the inflamed intestine is suppressed by Netrin-1

Measure of the inhibition rates of odorant molecules toward GSTM2 activity

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