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Given the advantages of small-molecule GLP-1RA, such as rapid diffusion, good BBB permeability and multiple modes of administration, small molecule compounds will be one of the important development trends of GLP-1RA

At the same time, North Carolina expanded Medicaid coverage to include GLP-1s for obesity treatment, recognizing the long-term cost savings associated with managing obesity-related conditions like heart disease and diabetes in older patients

A diabetes indication would open the usual Part D coverage for that condition

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