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*Correspondence: Mulugeta Woldeselassie, [email protected] Present address: Mulugeta Woldeselassie, Addis Ababa University, College of Natural and Computational Sciences, Center for Food Science and Nutrition, Addis Ababa, Ethiopia Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Future patent activity will likely need to shift toward formulation engineering, targeted delivery to reproductive tissues, and the development of semi-synthetic derivatives aimed at overcoming luteolins pharmacokinetic limitations