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Most side effects naturally improve with time as your body adapts

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If the appendix is located in the lower part of the abdomen, other symptoms could manifest as frequent urge to urinate, painful urination, an urge to empty the bowels, and diarrhea

The take-home message: The decision should be driven by the patient's clinical profile, cardiovascular disease, heart failure phenotype, CKD stage, renal function, albuminuria, guideline recommendations, and individual patient factors

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