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While human data remain limited, studies report wide variability in hepatocyte ploidy among individuals, ranging from 20-50% polyploidy [2, 51,52,53]
The goodness of fit was estimated using the coefficients of determination (r 2 )
Pan Afr Med J
Two main pathways can trigger this process, the intrinsic, also called mitochondrial pathway, when apoptosis is initiated by the internal signals of mitochondrial origin, and the extrinsic when apoptosis is activated by external stimuli [16]
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