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In addition to soluble cytokines, synovium-cartilage communication is increasingly recognized to be mediated by extracellular vesicles and exosomes carrying microRNAs, long non-coding RNAs, and bioactive proteins (Wessler and Meisner-Kober, 2025

J Trans Med (2022) 20(1):129

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Mesenchymal stem cell protection of neurons against glutamate excitotoxicity involves reduction of NMDA-triggered calcium responses and surface glur1 and is partly mediated by TNF