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An increase in ROS production or a decrease in ROS-scavenging capacity due to exogenous stimuli or endogenous metabolic alterations can disrupt redox homeostasis, lead to an overall increase intracellular ROS levels, or oxidative stress [29,30]

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Beyond its well-established antimicrobial properties, LL-37 exhibits various immunomodulatory effects, making it an intriguing target for therapeutic interventions (Lai & Gallo, 2009)

The American journal of emergency medicine

It boosts the anti-inflammatory ones, relieving common IBD symptoms