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So not only do we need to be aware of the acceptable lower limit, but also the acceptable upper limit which is currently not well defined
Concurrently, it is imperative to disentangle the concrete regulation on functional subgroups of the gut microbiota induced by metabolites from articular ferroptosis (for example, ROS and LPO) (such as probiotic genus composition, abundance of populations such as those of Lactobacillus and the Bacteroidetes/ Firmicutes ratio) and gut structural mucosal barrier integrity (for example, the expression of tight junction proteins, such as occludin and claudin)
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The lipids composition mainly include polyunsaturated fatty acids (PUFA) such as palmitic acid, -linolenic acid (GLA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) (Spnola et al
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