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Endocrine Practice, 29(1), 1723

These early changes typically include reduced appetite, fewer cravings, and improved digestive comfort

doi: 10.18632/oncotarget.4059 51

The trial sample size was chosen on the basis of the robust efficacy of ARA 290 in a rodent model of neuropathy (12) and from the observations derived from a prior small nonblinded trial of 20 patients with symptoms of SFN who received ARA 290 (2 mg intravenously) for three doses every 2 d over 1 wk (11)

Environmental design is one of the most powerful tools for sustaining behavior change, yet it is often overlooked in favor of willpower-based approaches