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The altered gut microbiome in Alzheimers disease can contribute to the development and progression of the disease through several interconnected mechanisms: Firstly, the dysbiotic microbiome can lead to increased intestinal permeability, allowing the translocation of bacterial metabolites, toxins, and inflammatory molecules into the systemic circulation

[DOI] [PubMed] [Google Scholar] Yokochi Y, Fukushi Y, Wakabayashi K, Yoshida K, Hisabori T

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IL-4 switches microglia/macrophage M1/M2 polarization and alleviates neurological damage by modulating the JAK1/STAT6 pathway following ICH