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Tirzepatide activates both GLP-1 and GIP receptors a dual mechanism that has shown stronger weight loss outcomes in head-to-head trials
whether the favourable profile observed in those cohorts extends to younger adults, to higher doses, or to continuous rather than pulsed administration is not established
This study also showed a strong correlation between high levels of AGEs and elevated glycated hemoglobin, or hemoglobin A1C a blood test that reflects average blood sugar levels over a 60- to 90-day period by measuring the amount of hemoglobin that has undergone glycation (Jakus 2014
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