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However, at 30 min and 60 min after H 2 O 2 exposure, the TmGst3 expression levels were no longer elevated

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This structural difference the removal of the Gly-Pro-Glu tripeptide has a profound effect on pharmacological behaviour

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Nonetheless, the common theme is that GLP-1 RAs tend to push the microbiome in a direction associated with metabolic health (greater abundance of SCFA-producing and mucus-associated bacteria, lower abundance of pro-inflammatory organisms), although substantial changes may require prolonged therapy (56)