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Together, our findings revealed a conserved susceptibility of DUBs to redox imbalance and provided insights into impaired deubiquitylation as a contributing factor to age-associated proteostasis decline

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At the end of the experiment, kidney and heart were isolated for histological and gene expression studies as well as for intrarenal RAS state assessment

The FDA label lists Type 2 diabetes and cardiovascular risk reduction in adults with Type 2 diabetes and established cardiovascular disease as approved uses

C., Smith, C