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Interestingly ATM deficient patients can sometimes present with early aging phenotypes including canities or with the pigment disorder vitiligo 56 and mice lacking ATM can also display coat and tail pigmentation abnormalities particularly after genotoxic insult 59

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Daniel Ghiyam unpacks the surprising science behind Melanotan, why regulators rejected it, and how researchers ultimately transformed one of its unexpected side effects into the FDA-approved womens health drug Vyleesi

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These advancements underscore that nanoparticles can precisely regulate TME, which is of great significance for personalised treatment [149]

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