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Alcohol-associated PAGln production and cardiovascular dysfunction are transmissible traits To address the relative contribution of alcohol-induced gut microbial reorganization towards increased PAGln levels and subsequent cardiovascular dysfunction, we performed microbial transplantation of gut commensals from PF and AF mice into nave mice using a previously reported protocol with modifications as described (Fig

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Using the five models with the lowest energies, geometries of the constructed loops were manually regularised in Coot 38