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L2-Cmu pharmacokinetic and chronic exposure assessments For PK studies, CB6F1 mice ( n = 45 per sex, per timepoint) were injected i.p
While the protection of normal cells against radiation-induced cell death by ebselen has been attributed to its ability to detoxify cellular/mitochondrial ROS through the GPx mechanism, the molecular mechanism contributing to its radio-sensitization effect in cancer cells is still not fully understood
Composed of 23 amino acids in a D-amino acid configuration, this cell-penetrating peptide represents a novel therapeutic approach to addressing cellular senescence, a fundamental driver of aging and age-related diseases
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Contamination during use introduces bacteria and enzymes that degrade peptides through proteolytic cleavage
