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For example, people who have conditions that increase the risk of iron overload or who are prone to kidney stones should be cautious with their vitamin C intake ( All the adverse effects of vitamin C, including digestive distress and kidney stones, appear to occur when people take it in doses greater than 2,000 mg ( If you choose to take a vitamin C supplement, its best to choose one that contains no more than 100% of your daily needs

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In www.ncbi.nlm.nih.gov

doi: 10.1016/j.molcel.2012.09.025 19

Circ_0000069 contributes to the growth, metastasis and glutamine metabolism in renal cell carcinoma (RCC) via regulating miR-125a-5p-dependent SLC1A5 expression