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intestinalis including gene products (highlighted in gray) contributing to the biosynthesis of glutathione [GCLC, GCLM, GSS, GGT1, xCT (SLC7A11)], its use as a redox buffer [GLRX, GPX1, GSR], and as a conjugate in phase II detoxification [GSTA1, GSTM1, GSTP1, MRP2 (ABCC2)], as well as known transcriptional regulators [NRF2 (NFE2l2), KEAP1, MAFF, BACH1, LXRA (NR1H3), FXR (NR1H4), and RXRA]

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Local injection (near the injury site) delivers maximum concentrations directly to damaged tissue

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Moreover, the results of metabolic studies have demonstrated the existence of a natural biosynthetic pathway whereby the methyl carbon atoms of dichlorvos can, with partial retention of hydrogen, become incorporated into the heterocyclic rings and the methyl groups of urinary 7-methylguanine after entering 1-C pools, in vivo