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Lancet Diabetes Endocrinol 9(4):212224

Epigenetically, phytochemicals, notably polyphenols and terpenoids, can alter histone acetylation and DNA methylation, as well as modulate miRNA expression, restoring silenced tumor suppressor genes and reducing oncogene expression, yielding antiproliferative, pro-apoptotic, and resensitizing effects (Dandawate et al., 2016

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CYP4A family, as the CYP family members, has been demonstrated to directly oxidize AA [39]

GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet