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No adverse events or treatment discontinuations were reported

Hormone therapy, for women who are eligible and within the timing window, remains the most comprehensively evidence-backed intervention for the full spectrum of perimenopausal symptoms including bone loss, cardiovascular risk reduction, cognitive protection, and quality of life

Finally, leaked electrons inevitably binds to the oxygen molecules and produces oxygen free radical and non-radical species in mitochondria as well as cytosol [25]

The inhibitory output interferes with the movement-related center in the thalamus and generates hypokinetic PD symptoms [73]