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The peptide has been studied in laboratory and preclinical settings and is used in cosmetics, but it has not completed the FDA drug-approval process for a medical indication

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Because an oral 15-PGDH inhibitor has already passed Phase 1 safety testing in humans for age-related #muscle weakness, the authors are hopeful that clinical trials in joint disease will follow, potentially paving the way for #nonsurgical, cartilage-regenerating therapies that could delay or replace knee and hip replacements

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