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To rigorously compare the effects of CDK11 inhibition and SNIP1 loss on splicing we compared fold changes of intron ratios between OTS964- and DMSO-treated HCT116 cells from our previous study 8 and between dTAG-induced SNIP1 depletion and DMSO control in dTAG SNIP1 HCT116 cells across 12727 protein-coding genes

The changes in alcohol-induced gut composition shows a decrease in beneficial bacteria and an increase in harmful bacteria