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Description

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The monomer unit has: N-terminal Glu-BD(Binding domain) that is composed mostly of -strands

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10.1073/pnas.90.23.11217 Proc

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In addition to ROS overproduction, the activation of MAPK and inactivation of phosphatidylinositol 3-kinase/Akt (a serine/threonine kinase that is also known as protein kinase B)/mammalian target of rapamycin (mTOR) are associated with both apoptosis and autophagy 6

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