do glp 1 change your metabolism Glucagon, GLP-1 and Thermogenesis Does GLP-1 Slow Down Metabolism?

They attached a long chain of lipids that can bind to albumin a protein in blood that serves as a carrier for the drugand keep the compound active for hours or even days

In both the intestinal epithelium and liver, they are rapidly transformed into hydrophilic metabolites through phase II enzymatic reactions such as glucuronidation, sulfation, and methylation, catalyzed by enzymes including uridine 5-diphospho-glucuronosyltransferase, sulfotransferase, and catechol- O -methyltransferase

Correlation analyses across these studies have consistently demonstrated positive associations between circulating prolactin concentrations and BMI, fasting glucose levels, insulin levels, and measures of insulin resistance

Protoplasma 252 (1), 209217

That same mechanism explains why a small subset of people may experience a temporary reduction in sexual motivation