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But they couldnt just reformulate cyclobenzaprine as a low dose oral pill

Thats a reasonable starting assumption, but it misses a few important considerations specific to this peptide

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Jastreboff et al., NEJM, 2022 (SURMOUNT-1) The Next Generation of Metabolic Medicine The efficacy and safety of Tirzepatide are supported by the extensive SURPASS and SURMOUNT clinical trial programs, heralding a new era in weight management