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On the other hand, several transcription factors, such as PPAR, PPAR and sterol regulatory element-binding protein-1 (SREBP-1), play an intermediary role in lipid homeostasis, by orchestrating the gene transcription of enzymes involved in this pathway ( Reference Spiegelman and Flier 13 )

Kybella is currently the only FDA-approved injectable fat dissolver

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The choice among the different members of this class depends on our clinical judgement considering the cardiovascular risk assessment, the GIT tolerance, the finance and the compliance of our patient