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In principle, that sustained tone could reduce both the frequency of eating occasions and the drive toward highly palatable foodthe two features most relevant to binge eatingbut the strength of this effect on genuine loss-of-control episodes, as opposed to ordinary appetite, is exactly what remains untested in BED
It is unknown whether Saxenda causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans, as the human relevance of liraglutide-induced rodent thyroid C-cell tumors has not been determined
And in animal experiments, what theyve done is theyve said, Okay, lets give these animals inhibitors of their mitochondria at specific locations and see what methylene blue does. And if you dont have any inhibitors, and if the animal is genetically healthy, then you add methylene blue, they get less ATP, so the mitochondria is less effective at converting food to usable energy
And they are involved in helping proteins keep their three-dimensional s-structure inside of your cells to prevent them from, uh, you know, aggregating and forming plaques
doi: 10.1016/j.pharmthera.2018.06.013 12 JiangHZhangXChenXAramsangtienchaiPTongZLinH
