With an updated formulation and new branding, oral semaglutide, now under the Ozempic name, helps patients and healthcare professionals more easily recognize the available FDA-approved treatment options for type 2 diabetes that contain the semaglutide molecule, said Michael Radin, MD, the executive medical director for Novo Nordisk
Basal insulin and sulfonylurea/glinide were discontinued at randomisation
This causes high oxidative stress, mitochondrial dysfunction, and cell death of the hepatocytes.[ref] As these cells die, inflammatory cascades perpetuate the oxidative stress, leading to bleeding, fibrosis, or possibly liver failure
It hasnt been further investigated to my knowledge
Stopping and restarting creates metabolic instability and often requires higher doses to re-achieve results