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Symptoms may include: Severe headache Neck stiffness Fever Nausea or vomiting Sensitivity to light (photophobia) Extreme fatigue These symptoms typically develop within several hours to a few days after an infusion

All data are representative of at least three independent experiments

It is important to mention that MD simulation under implicit solvent model has been marked as less reliable and detected with dissociation of ligand from the binding site in the receptor 106

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