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doi:10.1001/jamasurg.2015.1534 Coutinho M, Gerstein HC, Wang Y, Yusuf S

In order to further solidify their findings, the researchers analyzed the expression of the cell proliferation marker and the proliferating cell nuclear antigen (PCNA) in tendon fibroblasts at the RNA expression level through the use of RT-PCR

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La molcula no presenta homologa estructural con factores de crecimiento clsicos (VEGF, FGF, IGF-1), pero modula la expresin y actividad de mltiples sistemas trficos endgenos , posicionndola como agente pleiotrpico de proteccin y regeneracin tisular en investigacin experimental

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