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Important handling instructions include: remove the needle after each use, do not store with the needle attached, do not share pens with others, keep the pen cap on when not in use, visually check that the solution is clear and colorless before injection, and keep out of reach of children

Cloudiness, particles, discoloration, or separation indicate the medication should not be used

Activation of the GLP-1 receptor-mediated cAMP/PKA pathway is also involved in the protection of astrocytes from AGE-induced inflammatory response and from inflammatory cytokine secretion [83, 84]