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Marketing materials often assert that patches provide sustained release of berberine over extended periods (typically 824 hours), maintaining more stable blood concentrations compared to oral dosing

As with any medication, its important to weigh the potential benefits against the risks and consider each persons individual situation

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For many patients, the digestive system needs time to adapt to these physiological changes

Some macrogol preparations contain electrolytes, so patients on salt restriction or with heart failure should check with their pharmacist