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Summary By using various approaches and techniques, including KO mouse models, pharmacological compounds and expression of mutant proteins, Rho GTPases and their effectors have been shown to play essential roles in the regulation of spine formation, spine morphology, receptor trafficking and synaptic plasticity, and learning and memory
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In Phase 3 clinical trials, it produced unprecedented average weight reductions of up to 24% to 30% of body weight
GA: Conceptualization, Data curation, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing original draft, Writing review & editing
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