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Eur J Clin Pharmacol 69:851857 Kaddurah-Daouk R, Weinshilboum RM (2014) Pharmacometabolomics: implications for clinical pharmacology and systems pharmacology

Protective effects of NAMPT or MAPK inhibitors and NaR on Wallerian degeneration of mammalian axons

Among 56 enrolled congenital hypothyroid patients, the majority were suffering from dyshormonogenesis (50%, n = 28), whereas about 27% (n = 15), 9% (n = 5), 3% (n = 2) and 2% (n = 1) patients had etiologies of thyroid gland agenesis, thyroiditis, hypoplasia and ectopic thyroid gland, respectively (Table 2)

The anxiolytic effects induced by ghrelin likely involve the expression of ghrelin receptors in the nucleus accumbens and lateral septum, as ghrelin infusion into these brain regions decreases anxiety in mice and rats (70, 71)

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