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Some GLP-1 options have also demonstrated cardiovascular benefits, and newer incretin-based medications include dual-agonists (such as GIP/GLP-1) that work similarly but are not exactly the same drug class

While the C-terminus of oxyntomodulin and the receptor ECD/ECL1 was lower resolution in the cryo-EM map, the interaction patterns in the modelled protein and the MD simulations were largely similar to GLP-1, albeit that the nature of some interactions differed due to their differing sequences

Semaglutide FAQ Q: How much semaglutide should I take for weight loss

Meet the expert: Rekha Kumar, MD, is an endocrinologist at New York-Presbyterian and Weill Cornell Medicine

Sanin Syed, a dual board-certified specialist in both obesity medicine and internal medicine