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Consistency matters more than optimal timing

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Both UDCA and its taurine conjugate, tauroursodeoxycholic acid, have shown mitochondrial-enhancing, antioxidant, anti-inflammatory, and antiapoptotic effects in different preclinical PD models [76,77,78,79,80,81,82,83], as well as rescue of mitochondrial function in fibroblasts of people with PD [48, 84, 85]

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It has strong clinical evidence for weight loss when used as the FDA-approved obesity medication Wegovy at the appropriate dose