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Pineal peptides work best as part of a comprehensive sleep optimization strategy that includes appropriate light exposure (bright in morning, dim in evening), consistent sleep-wake times, cool sleeping environment (65 to 68 degrees Fahrenheit), limited stimulants after noon, and reduced screen exposure before bed

Clinical Evidence : Emerging clinical research supports NAD+ therapy for improving mitochondrial function, energy levels, and cognitive performance

Prasad A, Andrews NP, Padder FA, Husain M, Quyyumi AA

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Starting at lower doses and escalating gradually gives the body time to adapt without the full intensity of adjustment happening all at once