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The Journal of biological chemistry 287 , 4073240744, doi: 10.1074/jbc.M112.399899 (2012)

The effect of flaxseed supplementation on anthropometric indices, blood pressure, and lipid profile in diabetic patients: A GRADE-assessed systematic review and meta-analysis of randomized controlled trials

More substantial, clinically meaningful changes tend to accumulate by six months

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These events were generally mild to moderate , occurred predominantly during dose escalation, and often decreased in frequency or intensity as participants adapted to the target dose